TE is the biggest hole on the team.  Clark is no #1 and is a band-aid of a solution.  
Take a pass catcher and give Rex a bail out option over the middle.  

The only other #1 worthy pick is a CB.  Personally, I think the CB's haven't played that great overall.  Not to take anything away from Vasher, he catches anything around him, but a lot of his picks came on badly thrown balls, a credit to the pass rush.  Tillman can be great, but mixes it with a gambling style that gives up lots of deep balls.  

My breakdown of team needs follows:

Unit by Unit -
DL - Set (no picks)
LB - Backup would help (3rd or 4th rounder)
CB - Backup/Upgrade (2nd round/1st round)
S - Backup (3rd rd or later)

RB - Set (no picks)
WR - Most interesting argument, with Moose a lock and Bradley & Berrian emerging as solid 2/3 receivers, Currie getting healthy for the slot receiver job and Gage/Berlin a fine #5 receiver -A #3/4 Reciever in the draft would be okay, but more likely to be a solid #2 Free Agency Pickup.  This really could be a good, deep receiving corps next year (except Moose...zing!).  
TE - Most glaring need, (1st rounder).  Clark would be a great Red Zone threat as the 2nd TE in the formation.  
OL - Backup/Depth would be nice.  I like the move to extend Garza as a #1/2G&#2C.  Keep Terrence Metcalf as insurance for old and achy Ruben Brown, a solid OT would be good because whenever Tait or Miller goes down with a big injury things could get ugly with only St. Clair in the wings (I won't bother acknowledging Q. Mitchell and his 4 year deal).
QB - Set?  Sort of.  We have 3 and they'll all be back next year (Sorry, Kittner)

KR/PR - Berrian has done well as PR, but I wouldn't mind having someone else take those blind hits.  While we're at it, find someone who's a #1 KR and PR and use Berrian only if necessary.  
K/P - Gould is fine, Maynard was fine (sort of), but who knows what golden leg wonder is out there?

My guess at the draft:
Rd 1: TE
Rd 2: CB with solid return skills
Rd 3: OT
Rd 4: S
Rd 5: K/P/WR
Rd 6: LB
Rd 7: CB