I'm going to go ahead and set up the NFL Football Pick Em league on Yahoo! Simply give me your info and I will email you the league info.
For those who don't know, it works like this: Each week, you pick the team you think will win each game. If you get it right, you get a point, if you get it wrong, you don't. Yahoo just opened up to include playoffs, so this will go through the end of football season.
There are other options (confidence ranking, covering the point spread) but I usually just run a basic "right/wrong" system.